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. Author manuscript; available in PMC: 2019 Mar 15.
Published in final edited form as: J Proteome Res. 2018 Feb 12;17(3):1031–1040. doi: 10.1021/acs.jproteome.7b00657

Fig. 4. Dysregulated cell signaling in the NOS1/3−/− penis.

Fig. 4.

IPA for up- and down-regulated proteins in NOS1/3−/− penis yielded network interactions involving cell signaling kinases and G proteins. Protein expression determined by spectral counting is denoted by red (increased) and green (decreased) filled symbols. IPA determined predictions are denoted by orange (increased) and blue (decreased) filled symbols and connecting arrows. Solid arrows indicate direct action, hatched arrows indicate indirect action.