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. Author manuscript; available in PMC: 2019 Mar 15.
Published in final edited form as: J Proteome Res. 2018 Feb 12;17(3):1031–1040. doi: 10.1021/acs.jproteome.7b00657

Fig. 6. G-protein mediated effects on smooth muscle tone regulation.

Fig. 6.

(A) Canonical pathway for signaling by Rho family GTPases with activation predicted by the molecular activity predictor tool within IPA. Protein expression determined by spectral counting is denoted by red (increased) and green (decreased) filled symbols. IPA determined predictions are denoted by orange (increased) and blue (decreased) filled symbols and connecting arrows. (B) Western blot for the smooth muscle tone regulatory proteins MYPT1 and the smooth muscle isoform of MLC2. Beta-actin served as the loading control. Band densitometry was quantified and normalized to β-actin for n = 8 per group. * P < 0.05 vs. WT.