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. 2019 Mar 15;14(3):e0209392. doi: 10.1371/journal.pone.0209392

Fig 4. AMPKα activation with FND-4b increased apoptosis of breast cancer cells.

Fig 4

(A) Equal numbers of MCF-7, T-47D, MDA-MB-231, or HCC-1806 cells were cultured in medium containing different concentrations of FND-4b (0, 2.5, 5, and 10 μM) for 72 h before ELISA cell death assays were performed. (B) The basal apoptotic rates of MCF-7, T-47D, MDA-MB-231, and HCC-1806 cells were compared using the control data from the ELISA cell death assays in (A). Data are presented as mean ± SD from an experiment performed in triplicate and are representative of three independent experiments. * indicates p-value < 0.001.