. Author manuscript; available in PMC: 2019 Mar 15.

Published in final edited form as: J R Stat Soc Ser C Appl Stat. 2018 Nov 22;68(2):309–329. doi: 10.1111/rssc.12323

Table 1.

Dose-toxicity scenarios for simulation study. Combinations marked in bold have DLT probability of 20% ± 2%. Maximum Tolerated Contour (MTC) shown as solid line bisecting dose-toxicity grid.

	Drug A		Drug A
Scenario A		Scenario E
	Drug A		Drug A
Scenario B		Scenario F
	Drug A		Drug A
Scenario C		Scenario G
	Drug A
Scenario D