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. 2019 Mar 12;12:1957–1964. doi: 10.2147/OTT.S192631

Table 2.

Univariate Cox proportional hazard model for predictors of death

Variables β HR 95% CI P-value
Gender (male/female) −0.279 0.757 0.440–1.300 0.312
Age (≤60/>60, years) 0.101 1.107 0.716–1.710 0.647
Cirrhosis (+/−) −0.360 0.698 0.324–1.501 0.357
Tumor size (≤5/5, cm) 0.495 1.641 1.089–2.473 0.018
Tumor number (1/≥2) 0.800 2.225 1.549–3.198 <0.001
PVTT −0.764 0.466 0.314–0.691 <0.001
Child–Pugh (A/B) 0.294 1.341 0.780–2.305 0.288
BCLC (A/B/C) 0.391 1.478 1.211–1.804 <0.001
AFP (≤400/>400, ng/μL) 0.212 1.237 0.862–1.775 0.249
ALT (≤40/>40, U/L) 0.089 1.093 0.762–1.569 0.628
AST (≤40/>40, U/L) 0.454 1.574 1.036–2.391 0.034
ALP (≤150/>150, U/L) 0.583 1.791 1.206–2.660 0.004
GGT (≤50/>50, U/L) 0.443 1.557 1.008–2.405 0.046
PT (<11/11–14.3/>14.3, s) 0.305 1.357 0.953–1.933 0.091
Alb (<34/34–48/>48, g/L) −0.705 0.494 0.317–0.771 0.002
PA (≤200/>200, mg/L) −0.531 0.588 0.323–1.071 0.083
ApoA1 (<1.2/1.2–1.6/>1.6, g/L) −0.230 0.794 0.550–1.148 0.221
HDL-C (≤1.02/>1.02, mmol/L) −0.157 0.855 0.589–1.242 0.411
ApoB (<0.8/0.8–1.05/>1.05, g/L) 0.295 1.343 1.060–1.701 0.015
LDL-C (<2.07/2.07–3.12/>3.12, mmol/L) 0.180 1.198 0.922–1.556 0.177
TBA (≤9.67/>9.67, μmol/L) −0.072 0.930 0.637–1.359 0.708

Abbreviations: AFP, α-fetoprotein; ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate transaminase; Alb, albumin; ApoA1, apolipoprotein A1; ApoB, apolipoprotein B; BCLC, Barcelona Clinic Liver Cancer; GGT, g-glutamyl transpeptidase; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; PA, prealbumin; PT, prothrombin time; PVTT, portal vein tumor thrombus; TBA, total bile acid.