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Protein-wise peripheral blood mononuclear cell (PBMC) CD4+ T-cell responses to herpes simplex virus type 1 (HSV-1) in monozygotic (MZ) twins agree more than expected by chance. Data for unrelated persons were analyzed 5000 times by bootstrap analysis, with the percentage agreement shown as a histogram, with bins labeled on the x-axis. The observed agreement for presence or absence of protein-level CD4+ T-cell responses for the 10 MZ twin pairs was 80%.
