Table 1.
Demographic, Clinical, and Viral Coinfection Characteristics of Study Participants
| Characteristic | Overall (n = 102) | MZ Twins (n = 58) | DZ Twins (n = 44) |
|---|---|---|---|
| Twin pairs, no. | 51 | 29 | 22 |
| Zygosity confirmed by sex difference or DNA testing | 90 (88) | 54 (93) | 36 (82) |
| Age, y | 37 (19–78) | 30 (19–78) | 54 (19–72) |
| Sex | |||
| Male | 32 (31) | 16 (28) | 16 (36) |
| Female | 70 (69) | 42 (72) | 28 (64) |
| HSV-2 seropositive | 13 (13) | 4 (7) | 9 (20) |
| History of symptomatic HSV-1 | 87 (85) | 50 (86) | 37 (84) |
| Time since first symptoms of HSV-1, ya | 21 (0.083–68) | 21(0.25–68) | 32 (0.083–60) |
| HSV shedding rate,b % | 9 (0–47.4) | 9.2 (0–38.2) | 9.3 (0–47.4) |
| Days with oral lesions, % | 0 (0–23.4) | 0 (0–23.4) | 0 (0–23.3) |
| Asymptomatic shedding rate,b % | 7.1 (0–47.4) | 6.8 (0–25.5) | 7.8 (0–47.4) |
Data are no. (%) of twins or median value (range), unless otherwise indicated.
aFor participants with data available.
bSee Methods for the definition of shedding rate.