Table 2.

Plasma-Treated Cord Blood Endothelial Colony-Forming Cell (ECFC) Proliferative Capacity Functional Parameters of the 3 Study Groups

Characteristic	Uninfected (n = 15)	Infected, Untreated (n = 8)	Infected, Treated (n = 15)	P a
Network area, mm/mm2	0.11 ± 0.037	0.076 ± 0.031	0.10 ± 0.046	.018
Cell area, mm2/mm2	0.19 ± 0.034	0.14 ± 0.022b,c	0.18 ± 0.051	.0008
Network length, mm/mm2	2.62 ± 0.48	1.73 ± 0.43b,c	2.38 ± 0.56	<.0001
Network branch points, 1/mm2	7.27 ± 2.25	3.29 ± 1.54b	5.71 ± 2.86	<.0001
Average tube width, µm	42.39 ± 0.85	43.14 ± 0.60	42.88 ± 0.33	.023
Networks, 1/mm2	4.07 ± 0.36	3.80 ± 0.25c	4.42 ± 0.53	.0053
Average network length, mm/mm2	1.14 ± 0.33	0.94 ± 0.54	0.89 ± 0.18	.13
Average tube width uniformity	0.68 ± 0.0064	0.67 ± 0.0114b	0.68 ± 0.0060	.0028

Participants were human immunodeficiency virus (HIV) negative (uninfected group), HIV positive and not receiving antiretroviral therapy (ART; infected, untreated group), or HIV positive and receiving ART (infected, treated group).

^aValues of <.00625 were considered statistically significant for group differences across all 8 parameters. Values of <.00208 were considered statistically significant for pairwise comparisons for each individual parameter.

^bStatistically significant pairwise comparison for the infected, untreated group versus the uninfected group.

^cStatistically significant pairwise comparison for infected, untreated group versus the infected, treated group.