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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Free Radic Biol Med. 2018 Apr 23;127:116–123. doi: 10.1016/j.freeradbiomed.2018.04.560

Figure 2. Scheme of regulatory pathways and mechanisms for the diabetogenic potential of high Se intakes in comparison with adequate or deficient Se intakes in pigs and rodents.

Figure 2.

↑ Activation or increase; ↓ inhibition or decrease; Dio1, iodothyronine deiodinase 1; GPX1, glutathione peroxidase 1; GPX3, glutathione peroxidase 3; GPX4, glutathione peroxidase 4; Msrb1, selenoprotein X; SELENOH, selenoprotein H; SELENOP, selenoprotein P; Selenos, selenoprotein S; TXNRD1, thioredoxin reductase 1.