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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Photochem Photobiol. 2018 Oct 14;95(2):605–611. doi: 10.1111/php.13021

Figure 5. Baicalin treatment post chronic UVA radiation causes decrease in expression of TLR4 pathway and inflammatory biomarkers.

Figure 5.

Skin lysates were prepared from mice sacrificed at the termination of the experiment as described in the Materials and Methods section. A. Expression levels of TLR4, MyD88, IRAK4, TRAF6, COX-2, p47 were determined by western blot analysis in the skin lysates of baicalin and vehicle treated, and from unexposed and exposed skin mice. B. Bar diagram shows densitometric analysis of each band in the western blot. C-G. Expression level of TLR4, MyD88, TIRAP, COX-2 and iNOS were also determined by RT PCR as described in Materials and Methods section. There was a significant decrease in expression levels of TLR4, MyD88, TIRAP, COX-2, and iNOS (*p<0.05), in the skin of baicalin treated mice compared to the vehicle treated mice. N=5; experiment was repeated twice.