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. Author manuscript; available in PMC: 2020 Apr 1.

Published in final edited form as: Head Neck. 2019 Feb 18;41(4):857–864. doi: 10.1002/hed.25336

Table 4.

Multivariate analysis, accounting for group stage (per AJCC 8^th Ed.), correlating smoking history and age with OS, LRRFS, and DRFS.

	OS		LRRFS		DRFS
	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P
Any smoking	1.96 (1.2 – 3.1)	<0.01	1.23 (0.7 – 2.2)	0.42	1.32 (0.8 – 2.3)	0.33
10+ pack years	1.49 (1.0 – 2.3)	0.05	1.21 (0.7 – 2.1)	0.41	1.03 (0.6 – 1.7)	0.95
20+ pack years	1.26 (0.8 – 2.0)	0.38	1.06 (0.6 – 1.9)	0.93	1.02 (0.6 – 1.8)	0.98
Current smoking	1.10 (0.7 – 1.8)	0.72	0.78 (0.4 – 1.5)	0.43	1.04 (0.6 – 1.9)	0.88
Age (per year increase)	1.04 (1.0 – 1.1)	<0.01	1.03 (1.0 – 1.1)	0.03	1.02 (1.0 – 1.1)	0.14

Each row represents a separate Cox model. HR = hazard ratio. CI = confidence interval.