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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Traffic. 2019 Apr;20(4):284–294. doi: 10.1111/tra.12639

Figure 6: Simulation of kinesin-DDB bidirectional transport.

Figure 6:

DDB connotes activated complex containing one activated dynein. To model activated complexes like DDH and DDR that contain two dyneins, we carried out simulations with two DDB as a simplified model. A-B: Simulated traces for kinesin-1 versus (A:) one or (B:) two DDB complexes. Colors denote periods when only kinesin, only dynein, or both motors are attached. C: Velocity distributions over 5 second windows for kinesin-1 against one or two DDB complexes; distributions contain 5000 simulations. D-F: Identical panels for kinesin-2.