Figure 2.

Greater increases in IL-6 were significantly associated with greater increases in total response bias (i.e., reward responsiveness) from pre- to post-vaccine on the PRT (r = .40, p = .019) (Panel A). Analyses remain significant when removing the outlier on changes in total response bias (i.e., the participant with the highest values on the y axis in Panel A). The relationship between change in IL-6 and change in reward learning did not reach significance (r = .07, p = .710) (Panel B) nor did the association between change in IL-6 and change in reward sensitivity on the PRT (r = .28, p = .121) (Panel C). Note that reward sensitivity (logβ) and learning rate ($\log \left(\frac{\epsilon }{1-\epsilon }\right)$) parameters in the transformed space were used to prevent issues with non-Gaussianity.