Table 3.

Results from regression models predicting change in learning rate and change in reward sensitivity on the PRT from change in IL-6

Outcome	Predictor	b	β	SE	t	p-value	CI(lower)	CI (upper)
△Learning Rate
	△IL-6	1.06	.21	0.95	1.12	.274	−0.88	3.00
	BMI	0.003	.01	0.11	0.03	.977	−0.22	0.22
	Sex	−0.48	−.10	1.18	−0.41	.688	−2.89	1.94
	Cohort	−1.37	−.34	0.83	−1.66	.109	−3.06	0.32
	Intercept	0.69		4.14	0.17	.868	−7.79	9.17
△Reward Sensitivity
	△IL-6	0.31	.18	0.28	1.08	.288	−0.27	0.89
	BMI	−0.03	−.20	0.04	−0.76	.451	−0.12	0.05
	Sex	0.10	.07	0.22	0.46	.651	−0.36	0.56
	Cohort	0.09	.07	0.28	0.32	.751	−0.49	0.67
	Intercept	0.54		1.08	0.50	.620	−1.68	2.76

Note. IL-6= interleukin-6 (log transformed); BMI= Body Mass Index; △ = change (calculated as post-vaccine minus pre-vaccine). Learning rate($\log \left(\frac{\epsilon }{1-\epsilon }\right)$) and reward sensitivity (logβ) coefficients were derived from computational modeling of trial-level responses (Huys et al., 2013).