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. 2018 Oct 31;34(3):387–395. doi: 10.1007/s11606-018-4710-5

Table 2.

The Effects of ECHO Pain Clinician Participation on Prescribing of Opioids and Co-prescribing of Opioids and Benzodiazepines

Theme/variable Comparison baseline ECHO Pain baseline Comparison annual change percentage, P value ECHO Pain annual change percentage, P value Interaction P value
Opioid analgesic prescriptions (Rx)
 Avg. number of opioid RX/patient/year 0.86 0.31 − 9.2, P < 0.001 − 23.0, P < 0.001 0.004
 Avg. number of opioid RX/opioid user/year 1.61 2.27 − 0.6, P < 0.001 − 1.8, P = 0.36 0.41
 Percent opioid users 53.56 13.69 − 8.0, P < 0.001 − 20.2, P < 0.001 < 0.001
Morphine milligram equivalents (MME)
 Avg. MME/patient/year 363.95 171.57 − 7.3, P < 0.001 − 28.0, P = 0.002 0.02
 Avg. MME/opioid user/year 679.53 1253.14 + 1.1, P = 0.30 − 6.2, P = 0.33 0.32
 Percent opioid users 53.56 13.69 − 8.0, P < 0.001 − 20.2, P < 0.001 < 0.001
Co-prescribing opioids and benzodiazepines
 Days of co-Rx/patient/year 0.54 0.36 − 9.6, P < 0.001 − 68.9, P < 0.001 < 0.001
 Percent patients who are co-Rx users 3.26 1.22 − 8.5, P < 0.001 − 68.9, P < 0.001 < 0.001
 Days of co-RX/opioid user/year 1.01 2.65 − 1.3, P = 0.41 − 53.3, P = 0.002 < 0.001
 Percent opioid users who are co-Rx users 6.09 8.92 − 0.2, P = 0.82 − 26.6, P = 0.002 < 0.001

Average annual percent change over the study period in comparison and ECHO Pain groups for several outcome measures concerning opioid use (listed in the left column). Average annual change refers to regression slopes per year in the Repeated Measures (RM) ANCOVA analyses; negative slopes indicate decline. Average baseline values (of the outcome variable listed in the corresponding row) are in the second and third columns for comparison and ECHO Pain groups, respectively. The fourth and fifth columns contain the annual % changes (slopes) and P values testing whether there was any change over time within a group. The final column contains the interaction P values testing whether the two slopes for comparison and ECHO Pain groups differ and indicating whether the ECHO Pain intervention was effective