Table 1.
Clinicopathological characteristics of patients with PD-L1-negative and PD-L1-positive gastric cancer.
| PD-L1 | p value | ||
|---|---|---|---|
| Negative (n = 239) | Positive (n = 44) | ||
| Age (years) | 66.5 ± 11.8 | 68.9 ± 8.8 | 0.2009 |
| Sex | |||
| male | 152 (64%) | 36 (82%) | 0.0187 |
| female | 87 (36%) | 8 (18%) | |
| Histological type | |||
| intestinal | 123 (51%) | 31 (70%) | 0.0201 |
| diffuse | 116 (49%) | 13 (30%) | |
| Lymphatic invasion (ly) | |||
| negative | 78 (33%) | 4 (9%) | 0.0014 |
| positive | 159 (67%) | 40 (91%) | |
| Venous invasion (v) | |||
| negative | 117 (49%) | 13 (30%) | 0.0154 |
| positive | 120 (51%) | 31 (70%) | |
| Tumor location | |||
| upper third | 51 (21%) | 15 (34%) | 0.0660 |
| middle or lower third | 188 (79%) | 29 (66%) | |
| Depth of tumor invasion (T) | |||
| 1 | 95 (40%) | 8 (18%) | 0.0063 |
| 2, 3, 4 | 144 (60%) | 36 (82%) | |
| Lymph node metastasis (N) | |||
| 0 | 126 (53%) | 17 (40%) | 0.0946 |
| 1, 2, 3 | 110 (47%) | 26 (60%) | |
| Stage | |||
| I | 110 (46%) | 12 (28%) | 0.0258 |
| II, III, IV | 128 (54%) | 31 (72%) | |
| MSI | |||
| non-MSI | 226 (95%) | 35 (80%) | 0.0006 |
| MSI | 13 (5%) | 9 (20%) | |
| EBV | |||
| negative | 221 (92%) | 39 (89%) | 0.3926 |
| positive | 18 (8%) | 5 (8%) | |