Table 2.
Negative predictive biomarker candidates for cardiac differentiation of hiPSC lines.
| Gene name | Analysis | Entrez gene name | Role in cell |
|---|---|---|---|
| ZNF229 | CAGE & mRNA | zinc finger protein 229 | unknown |
| PLCB1 | mRNA | phospholipase C beta 1 | differentiation, expression in, activation in, cell death, G2/M phase transition, loss, binding, size, hypertrophy, fusion |
| TMEM64 | mRNA & miRNA | transmembrane protein 64 | differentiation |
| PTGR1 | CAGE | prostaglandin reductase 1 | survival |
| FOXQ1 | CAGE | forkhead box Q1 | formation by, expression in, quantity, migration, proliferation |
| MYL4 | CAGE | myosin light chain 4 | unknown |
| FGF17 | CAGE & miRNA | fibroblast growth factor 17 | proliferation, abnormal morphology, phosphorylation in, survival |
| GATA6 | CAGE & miRNA | GATA binding protein 6 | differentiation, expression in, proliferation, apoptosis, transcription in, transactivation in, specification, growth, abnormal morphology |
| ANKRD1 | CAGE & miRNA | ankyrin repeat domain 1 | apoptosis, response, differentiation, cell viability, expression in, colony formation |
| IGFBP5 | CAGE & miRNA | insulin like growth factor binding protein 5 | growth, migration, apoptosis, proliferation, survival, translation in, differentiation, cell spreading, expression in, quantity |
| WNT3 | CAGE | Wnt family member 3 | expression in, binding in, accumulation in, signaling in, transcription in, phosphorylation in, proliferation, differentiation, stabilization in |
| IGF2 | CAGE | insulin like growth factor 2 | proliferation, differentiation, growth, migration, phosphorylation in, apoptosis, expression in, activation in, survival, quantity |