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. 2019 Jan 18;67(2):125–131. doi: 10.1007/s00005-019-00534-9

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© The Author(s) 2019

OpenAccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 3 — Effect of fucoidan on cell cycle progression in SK-UT-1 (a), SK-UT-1B (b), ESS-1 (c) and MES-SA (d) cell lines. The cell lines were incubated for 48 h with fucoidan (0.05–5 mg/ml) and analyzed by flow cytometry. The results are presented as mean ± SD from three separate experiments. Data were analyzed by flow cytometry and results are expressed as mean ± SD of three separate experiments (n = 6 per each concentration; *p < 0.05, **p < 0.01, ***p < 0.001 versus the control, one-way ANOVA test)