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. 2019 Mar 15;9:4614. doi: 10.1038/s41598-018-37501-x

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Tissue expression of the two most differentially expressed genes between DcnKO and WT C57BL/6J mice. Global gene expression was measured in iWAT by Illumina microarrays, revealing Prtn3 and Hal as the most down- and up-regulated genes, respectively, comparing dcnKO and WT mice. mRNA expression levels of Prtn3 (A) and Hal (B) in different metabolic tissues were measured by qPCR and calculated relative to the reference gene Rps13. iWAT, inguinal white adipose tissue; eWAT, epididymal white adipose tissue; BAT, interscapular brown adipose tissue. *p-value < 0.05; **p-value < 0.01; *p-value < 0.001.

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