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ELTD1 expression ex vivo significantly decreased in G55 glioma tissue in anti-VEGFR2 Ab treated mice. SA-HRP staining of the ELTD1 probe (via the biotin moiety) in untreated G55 tumors (A), compared to anti-VEGFR2 Ab treated glioma tissue (B). (C) Percent positivity for the ELTD1 probe was significantly reduced in anti-VEGFR2 Ab-treated gliomas, compared to untreated tumors (P < 0.01). Mean ± SD, n = 5.
