Table 2.
Class differences in symptom severity at 36 months
| ANOVA | Post hoc Tukey’s tests | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Class 2 vs. class 1 | Class 3 vs. class 1 | Class 3 vs. class 2 | |||||||
| F | dof | p | t | p | t | p | t | p | |
| ADOS at 36m1 | |||||||||
| CSS-Tot | 1.77 | 2/232 | 0.17 | – | – | – | – | – | – |
| CSS-SA | 1.04 | 2/232 | 0.35 | – | – | – | – | – | – |
| CSS-RRB | 2.15 | 2/232 | 0.12 | – | – | – | – | – | – |
| ADI-R at 36m2 | |||||||||
| ADI-Comm3 | 9.56 | 2/236 | < 0.001* | − 4.25 | < 0.001* | − 3.97 | < 0.001* | − 0.42 | 0.91 |
| ADI-Soc3 | 13.0 | 2/236 | < 0.001* | − 5.04 | < 0.00* | − 4.39 | < 0.001* | 0.01 | 1.00 |
| ADI-RBI4 | 5.32 | 2/236 | 0.005* | − 2.79 | 0.015* | − 3.23 | 0.004* | − 1.28 | 0.40 |
| SCQ at 36m2 | |||||||||
| SCQ-Tot3 | 11.2 | 2/236 | < 0.001* | − 4.40 | < 0.001* | − 4.53 | < 0.001* | 0.50 | 0.50 |
This table shows the detailed statistics from the ANOVA-investigated differences between classes in symptom severity at 36 months as measured by the ADOS, ADI-R, and SCQ. When differences were significant, post hoc Tukey’s tests for multiple comparisons were performed for paired comparisons of classes. Differences were considered significant for p < 0.05 (marked as “*”)
ANOVA analysis of variance, Class 1 decreasing adaptive behaviour, Class 2 average/stable adaptive behaviour, Class 3 recovering adaptive behavior, dof degrees of freedom, ADOS Autism Diagnostic Observation Schedule, CSS Calibrated Severity Score, ADI-R Autism Diagnostic Interview-Revised, SCQ Social Communication Questionnaire
1Data were available for a subsample of n = 235 infants
2Data were available for a subsample of n = 239 infants
3Significant difference per class with p < 0.001
4Significant difference per class with p < 0.05