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JHMV replicates in glial cells derived from mouse NPCs. A: Differentiated progenitor cultures were infected with JHMV (multiplicity of infection = 0.1) and viral titers in supernatants determined at 12, 24, and 48 hr postinfection (p.i.) by plaque assay. B: Immunocytochemical staining for viral antigen at 24 hr p.i. revealed wide-spread distribution of virus throughout the cell culture (100 × magnification). Figures derived from Whitman et al. 2008.
