. Author manuscript; available in PMC: 2019 Dec 1.

Published in final edited form as: DNA Repair (Amst). 2018 Sep 20;72:56–63. doi: 10.1016/j.dnarep.2018.09.008

Table 1.

k_obs Values and Product Yield for U:G in Duplex DNA and NCP.

Enzyme	Substrate	k_obs min⁻¹ (Fraction product)^a
UDG	Duplex	24.9 ± 1.2 (0.98)
	NCP	5.7 ± 0.4 * (0.98)
SMUG1	Duplex	2.1 ± 0.1 * (0.99)
	NCP	1.1 ± 0.6 * (0.04)	(4.9 ± 4.2)×10⁻³ * (0.21)
TDG^FL	Duplex	6.2 ± 0.4 * (0.98)
	NCP	3.4 ± 0.9 * (0.09)	0.03 ± 0.01 * (0.62)
TDG^82-308	Duplex	7.2 ± 1.7 * (0.98)
	NCP	1.2 ± 0.2 * (0.18)	0.04 ± 0.01 * (0.65)

Rates reported as mean ± standard error (n=3 for duplex substrates, TDG^82-308 NCP; n=4 for UDG, SMUG1, TDG^FL NCP substrates). Asterisk (*) denotes p<0.01 compared to UDG duplex.