Table 4.
Mean EDSS disability scores and change in EDSS scores since inclusion in patients continually taking GA
| Duration of follow-up | N a | n1b | Mean ± SD | Change in EDSS score from inclusion | |||||
|---|---|---|---|---|---|---|---|---|---|
| n2c | Mean ± SD | ≤ 0 | + 0.5 | + 1 or 1.5 | ≥ 2 | ||||
| Inclusion | 395 | 324 | 2.1 ± 1.6 | – | – | ||||
| 12 months | 395 | 379 | 1. 9 ± 1.6 | 315 | − 0.10 ± 0.76 | 258 (81.9%) | 25 (7.9%) | 27 (8.6%) | 5 (1.6%) |
| 24 months | 337 | 308 | 2.0 ± 1.7 | 257 | 0.11 ± 0.93 | 175 (68.1%) | 33 (12.8%) | 33 (12.8%) | 16 (6.2%) |
| 36 months | 308 | 274 | 2.1 ± 1.7 | 231 | 0.16 ± 1.09 | 147 (63.6%) | 27 (11.7%) | 36 (15.6%) | 21 (9.1%) |
| 48 months | 291 | 262 | 2.1 ± 1.7 | 219 | 0.22 ± 1.04 | 137 (62.6%) | 20 (9.1%) | 41 (18.7%) | 21 (9.6%) |
| 60 months | 269 | 243 | 2.0 ± 1.8 | 207 | 0.21 ± 1.11 | 139 (67.1%) | 13 (6.3%) | 35 (16.9%) | 20 (9.7%) |
aAll patients available for analysis at each annual time-point
bPatients whose baseline EDSS score was determined at least 3 months from an exacerbation
cPatients whose EDSS scores at baseline and at the follow-up visit were both determined at least 3 months from an exacerbation