Table 2.
| % of surface occupied by 4-HNE positive cells in liver parenchyma after 4 days | % of surface occupied by 4-HNE positive cells in liver parenchyma after 1 month | % of surface occupied by 4-HNE positive cells in liver parenchyma after 2 months | |
|---|---|---|---|
| Controls | - | - | - |
|
| |||
| TiO2 0.5g/kg BW | - | - | - |
|
| |||
| TiO2 1g/kg BW | 0.07 ± 0.03 | 0.05 ± 0.04 | 0.12 ± 0.03 |
|
| |||
| TiO2 4g/kg BW | 0.83 ± 0.34 | 0.78 ± 0.28 | 1.02 ± 0.45 |
|
| |||
| TiO2 16g/kg BW | 3.83 ± 1.04 | 4.25 ± 1.53 | 4.17 ± 1.67 |
% of area occupied by 4-hydroxynonenal (4-HNE) in liver parenchyma evaluated by morphometric analysis. Values indicate mean percentage ± standard deviation (SD).