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. 2019 Mar 14;7:e6555. doi: 10.7717/peerj.6555

Figure 2. Correlation of Blue module with clinical stage.

Figure 2

(A) Bar plot of mean gene significance across genes associated with ACC stage in the module. (B) Heat map with each cell containing the p-value correlation from the linear mixed-effects model. Row corresponds to module; column corresponds to ACC clinical traits. Results indicate that MEblue is highly related to patient stage. (C) The dendrogram shows the relation of modules with stage and the heatmap shows the eigengene adjacency. (D) Correlation between MEblue membership and gene significance. (E) GO enrichment analysis of 650 genes in MEblue identified biological processes related to cell proliferation. Y-axis represents significance of enrichment results transformed to “−log(p-value).” (F) KEGG enrichment analysis of 650 genes in MEblue identified pathways related to cell cycle and DNA replication.