Table 3. List of genes regulated by HOXC6 in Eca109 and TE10 stable cells.

Gene		Description of function	Cancer type	Reference
Eca109-up	MMP14	Promote cell migration and invasion	Nasopharyngeal carcinoma	Yan et al. (2015)
		Promote tumor invasion and angiogenesis	Pituitary adenomas	Hui et al. (2015)
	SATB1	Promote cell growth and invasion	pancreatic cancer	Chen et al. (2015)
		Promote cell growth and invasion	Prostate cancer	Mao et al. (2013)
		Promote cell invasion and metastasis	Breast cancer	Han et al. (2008)
	AKAP9	Promote proliferation, migration and invasion	Colorectal cancer	Yang et al. (2015)
		Promote proliferation, migration and invasion	Colorectal cancer	Hu et al. (2016)
	CFH	Promote proliferation and migration	Cutaneous squamous cell carcinoma	Riihila et al. (2014)
		Promote tumorsphere formation	Liver cancer	Seol et al. (2016)
	JAK2	JAK2 inhibition prevents cell migration and invasion	Glioblastoma	Senft et al. (2011)
		JAK2 inhibition suppresses cell migration, invasion and proliferation	Cervical cancer	Luo et al. (2016)
TE10-up	SPARC	Promote cell invasion and growth	Gastric cancer	Yin et al. (2010)
		Promote cell proliferation, invasion and metastasis, induced cell apoptosis	Ovarian cancer	Chen et al. (2012a)
	FN1	Promote proliferation, migration and invasion	Thyroid cancer	Sponziello et al. (2016)
		Promote proliferation, migration and invasion	Gastric cancer	Zhang et al. (2017)
	WNT6	Promote proliferation, cell cycle and migration, but inhibit cell apoptosis	Colon cancer	Zheng & Yu (2018)
		Inhibit cell apoptosis	Gastric cancer	Yuan et al. (2013)
Common-up	SEMA3C	Promote tumor growth and metastasis	Pancreatic ductal adenocarcinoma	Xu et al. (2017)
		Promote the survival and tumorigenicity of glioma stem cells	Glioma	Man et al. (2014)
		Promote adhesion, invasion and proliferation	Breast cancer	Malik et al. (2016)
	INHBA	Promote cell proliferation	Lung adenocarcinoma	Seder et al. (2009b)
		Promote cell proliferation	Esophageal adenocarcinoma	Seder et al. (2009a)
	SGK1	Promote cell proliferation and migration	Colorectal cancer	Liang et al. (2017)
		Promote cell proliferation	Colorectal cancer	Lang, Perrotti & Stournaras (2010)
	HEY1	Promote cell invasion and metastasis	Osteosarcoma	Tsuru et al. (2015)
		Promote proliferation	Glioblastoma	Hulleman et al. (2009)