Table A1.
Frequencies | |||||||||
---|---|---|---|---|---|---|---|---|---|
Full siblings | Maternal half-siblings | Tetrachoric correlation | |||||||
Cases | Controls | Prevalence (%) | Cases | Controls | Prevalence (%) | Full sibs | Maternal half-sibs | h2 | |
Alcohol dependence | 87 773 | 3 043 417 | 2.80 | 10 589 | 157 287 | 6.31 | 0.253 (0.004) | 0.142 (0.012) | 0.444 (0.052) |
Anorexia nervosa | 8067 | 3 123 123 | 0.26 | 657 | 167 219 | 0.39 | 0.207 (0.020) | 0.120 (0.076) | 0.349 (0.316) |
Attention deficit hyperactivity disorder | 5003 | 209 959 | 2.33 | 895 | 8927 | 9.11 | 0.445 (0.014) | 0.175 (0.040) | 0.852 (0.171) |
Autism spectrum disorder | 2430 | 212 532 | 1.13 | 237 | 9585 | 2.41 | 0.388 (0.022) | 0.055 (0.098) | 0.665 (0.402) |
Bipolar disorder | 18 655 | 3 112 535 | 0.60 | 1619 | 166 257 | 0.96 | 0.303 (0.009) | 0.167 (0.038) | 0.543 (0.158) |
Major depressive disorder | 121 015 | 3 010 175 | 3.86 | 12 377 | 155 499 | 7.37 | 0.194 (0.004) | 0.117 (0.011) | 0.307 (0.048) |
Obsessive compulsive disorder | 11 553 | 3 119 637 | 0.37 | 1003 | 166 873 | 0.60 | 0.228 (0.014) | 0.167 (0.048) | 0.244 (0.198) |
Schizophrenia | 15 178 | 3 116 012 | 0.48 | 1106 | 166 770 | 0.66 | 0.330 (0.010) | 0.050 (0.058) | 0.569 (0.049) |
Note. Standard errors are presented in parentheses.
Sex and age was regressed out from all disorders.
For ADHD and Autism, birth year was limited to 1990 or higher.
Youngest sibling born at age 20 or later.