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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: J Eukaryot Microbiol. 2018 Oct 5;66(3):460–468. doi: 10.1111/jeu.12690

Fig. 2. Identification of four known compounds as inhibitors of CpHK.

Fig. 2.

(A) Screening of the Prestwick chemical library containing 1200 marketed drugs at 20 μM (green round circles) showing specific hits (red round circles) and non-specific hits (triangles). 2-deoxy-D-glucose at 0.5 mM was used as a positive control. (B) Hit validation assay showing that the four drugs were authentic hits because they were ineffective on G6PDH used in the CpHK/G6PDH-coupled assay. Bars represent standard errors of the mean (SEMs) derived from at least three replicated reactions.