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In vitro efficacy of 2-deoxy-D-glucose (2DG), 2-deoxy-D-glucose-6-phosphate (2DG6P) against the growth of C. parvum (44 h infection assay) and cytotoxicity on the HCT-8 cells (44 h treatment)
| Inhibitor | In vitro efficacy (EC50, mM) | Cytotoxicity (TC50, mM) |
Safety Interval (TC50/EC50) | |||
|---|---|---|---|---|---|---|
| 2DG | 0.54 | 36.0 | 66.7 | |||
| 2DG6P | 18.0 | >72.0 | >4.0 | |||
| 2FDG | 0.30 | >72.0 | >240 | |||
