Substrain and sex differences in infarct size after tandem MCA/CCA
occlusion. (a) Substrain differences. For both males and females, J
and ByJ substrains exhibited smaller infarcts than NCrl and NJ mice
(*, P < 0.05 vs. both N substrains). (b) Sex
differences. Mean infarct volumes were identical for males and
females of NJ and NCrl substrains, but J and ByJ females had smaller
infarcts than their male counterparts (*,
P < 0.05, male vs. female). Line indicates
identity. Group sizes for J, ByJ, NCrl and NJ substrains were 25,
21, 23 and 15 for males and 38, 14, 12 and 20 for females,
respectively.