Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Mar 11;10:402. doi: 10.3389/fimmu.2019.00402

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Ramadani, Bowen, Gould and Fear.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Distinct gene expression patterns and identification of genes unique different stages of B cell differentiation into PCs. (A) Clustering of genes differentially expressed along the differentiation pathway of B cells into PCs regardless of the Ig isoform was undertaken by the production of unsupervised Self-organizing Maps (SOM). (B) Venn diagrams showing overlaps and differences between genes that were significantly (p < 0.05) up-regulated or down-regulated by >1.5-fold in IgE⁺ cells along their differentiation pathway into PCs. (C) Venn diagrams showing overlaps and differences between genes that were significantly (p < 0.05) up-regulated or down-regulated by >1.5-fold in IgG1⁺ cells along their differentiation pathway into PCs.