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. 2019 Mar 11;12:58. doi: 10.3389/fnmol.2019.00058

FIGURE 4.

FIGURE 4

Effects of L-Cys on NF-κB activation, JNK and p38 phosphorylation in the ipsilateral cortex at 72 h post-HI. (A) Representative immunoblots are shown for phosphorylated NF-κB (p-NF-κB), total NF-κB, phosphorylated-IκBα (p-IκBα) and total IκBα as determined with western blotting analysis. Quantification of relative levels of p-NF-κB, NF-κB, p-IκBα and IκBα in each group. Values were normalized to β-actin. N = 4 mice/group. (B) Representative immunoblots of phosphorylated JNK (p-JNK), total JNK, phosphorylated-p38 (p-p38) and total p38 protein levels using western blotting analysis. Quantification of relative levels of p-JNK/JNK and p-p38/p38 in each group. N = 4 mice/group. Values represent the mean ± SD, ∗∗p < 0.01, ∗∗∗p < 0.001 HI vs. Sham; #p < 0.05, ##p < 0.01, HI + L-Cys vs. HI; &p < 0.05, &&p < 0.01 HI + L-Cys + AOAA vs. HI + L-Cys.