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. 2019 Mar 11;12:58. doi: 10.3389/fnmol.2019.00058

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Copyright © 2019 Zhou, Chu, Xin, Li, Bai, Qiu, Yuan, Liu, Wang and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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L-Cys attenuates HI-induced brain injury via AMPK activation. (A) Representative brain photographs as determined at 72 h following HI. Arrows indicate sites of significant edema. Brain water content was determined at 72 h following HI insult, N = 5 mice/group. (B) Representative samples stained with TTC. Infarct volume (white area) was quantified. N = 5 mice/group. Values represent the mean ± SD, ^∗∗∗p < 0.001 HI vs. Sham; ^##p < 0.01, ^###p < 0.001 HI + L-Cys vs. HI; ^&&p < 0.01 HI + L-Cys + CC vs. HI + L-Cys.