Table 1.

Percentage of change in pO₂ and iqr over a period of 90 d

Mice	% Δ(pO2)	% Δ(iqr)
0.5-mm capsules
Healthy mice
Mouse 1	−15.8	51.2
Mouse 2	−28.2	−26.7
Mouse 3	−26.5	−29.8
Mouse 4	−42.0	−40.8
Mouse 5	−34.4	−26.3
Diabetic mice
Mouse 1	−4.7	30.6
Mouse 2	−14.7	−38.1
Mouse 3	−15.7	−47.3
Mouse 4	−19.2	−52.1
Mouse 5	−22.6	−48.9
1.5-mm capsules
Healthy mice
Mouse 1	−2.5	187.1
Mouse 2	12.3	27.4
Mouse 3	−14.1	−21.3
Mouse 4	9.4	6.2
Mouse 5	−0.6	−29.2
Diabetic mice
Mouse 1	−1.2	156.2
Mouse 2	6.5	5.1
Mouse 3	0.4	10.2
Mouse 4	−0.9	−13.1
Mouse 5	0.4	29.9

Each row corresponds to an individual mouse from each of the four groups studied. For 0.5-mm capsules, decrease in pO₂ over time is accompanied by decrease in capsule dispersity for both islet-containing (diabetic mice) and empty (healthy mice) capsules, with the exception of one healthy mouse. For 1.5-mm capsules, no consistent trend across each animal group can be observed. pO₂ and iqr values are calculated over 12 image slices for each mouse. Each MRI measurement is the average of two acquisitions.