Fig. 5.

Formation of dynamic contact hub depends on epigenetic features. (A) Number of contacts observed in HOXC fiber system between LH/LH (teal), LH/Ac (pink), Ac/Ac (red), LH/NFR (blue), Ac/NFR (green), and any interaction that involves unmodified regions (WT; gray) as a function of genomic position. (B, Left) Plot of average pairwise distance count between gene promoters in the HOXC system vs. two reference systems. (B, Right) Renderings of chromatin configurations with promoter contacts (green/yellow highlight).