Table 3:
Variables | EVLP | Control | P-value |
---|---|---|---|
Number of patients | 54 | 271 | |
Single lung transplantation, n (%) | 7 (13) | 37 (14) | |
Bilateral sequential lung transplantation (including one bilobar LTx), n (%) | 47 (87) | 234 (86) | |
Intraoperative ECC/ECMO, n (%) | 29 (54) | 125 (46) | |
PaO2/FiO2 at arrival in ICU (kPa), mean ± SD | 30 ± 14 | 36 ± 14 | 0.005 |
Time to extubation (h), median (range) | 18 (2–912) | 7 (0–2280) | 0.002 |
ICU stay (days), median (range) | 4 (2–65) | 3 (1–156) | 0.002 |
Time to discharge (days), median (range) | 30 (17–112) | 28 (12–268) | 0.35 |
FEV1% at 12 months, mean ± SD | 75 ± 29 | 81 ± 26 | 0.18 |
1-Year survival | 87% (CI 82–92%) | 83% (CI 81–85%) |
CI: confidence interval; ECC: extracorporeal circulation; ECMO: extracorporeal membrane oxygenation; EVLP: ex vivo lung perfusion; FEV1: forced expiratory ventilation in the 1 s; ICU: intensive care unit; LTx: lung transplantation; PaO2/FiO2: arterial oxygen tension/inspired oxygen fraction; SD: standard deviation.