Table 3. Pharmacokinetic Properties and Cellular Activity of Compound 19^a.

IC50 [μM]	PKC-ι	0.34
GI50 [μM]	Huh-7	11.3
in vitro PK	Sol (pH 7.4, μg/mL)	164
	Caco-2 (A–B, 10–6 cm/s)	0.28
	MLM/HLM (CL, μL/min/mg)	71/5.1

^aPKC-ι inhibitor CRT0066854¹² was used as a positive control; GI₅₀ against HUH-7 cells was 3.1 μM.