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Structures of known NMDAR channel blockers and negative allosteric modulators; memantine (1), dextromethorphan (2), amantadine (3), ketamine (4) ifenprodil (5),8,9 DQP-110511 (6), QNZ-4610 (7), NAB-1415 (8), TCN-20113 (9, a GluN2A-selective negative allosteric modulator that acts by reducing glycine affinity), and EVT-101 (10).16
