Table 3.
Association between maternal organochlorine pesticide exposure and communication development scores in daughters at 15 months by strata of parity.*
| Nonverbal Communication |
Social Development |
Verbal Comprehension | Vocabulary Comprehension & Production |
|||||
|---|---|---|---|---|---|---|---|---|
| Analyte Tertiles (ng/g lipid) | Adjusted mean (95% CI) |
P*** | Adjusted mean (95% CI) |
P*** | Adjusted mean (95% CI) |
P*** | Adjusted mean (95% CI) |
P*** |
| Nulliparous women | ||||||||
| HCB (n = 189) | ||||||||
| 1 ( ≤ 41.2) | 14.56 (13.75, 15.37) | 18.05 (16.53, 19.57) | 0.07 | 9.96 (9.37, 10.55) | 113.39 (101.28,125.49) | |||
| 2 (41.21–59) | 15.32 (14.67, 15.98) | 0.16 | 19.29 (17.95, 20.63) | 0.07 | 10.10 (9.58, 10.62) | 0.01 | 103.02 (92.34, 113.70) | 0.11 |
| 3 (> 59.0) | 14.02 (13.32, 14.73) | 0.89 | 17.32 (15.67, 18.97) | 0.56 | 8.97 (8.33, 9.61) | 0.04 | 88.99 (75.85, 102.12) | 0.01 |
| p-trend** | 0.90 | 0.56 | 0.04 | 0.01 | ||||
| Parous women | ||||||||
| HCB (n=187) | ||||||||
| 1 ( ≤ 41.2) | 15.07 (14.13, 16.01) | 18.63 (17.13, 20.13) | 9.51 (8.87, 10.16) | 97.43 (85.90, 108.96) | ||||
| 2 (41.21–59) | 15.05 (14.17, 15.93) | 0.26 | 19.44 (18.04, 20.85) | 0.43 | 9.65 (9.05, 10.25) | 0.73 | 87.01 (76.21, 97.80) | 0.91 |
| 3 (> 59.0) | 14.30 (13.36, 15.24) | 0.28 | 18.61 (17.13, 20.13) | 0.99 | 9.50 (8.86, 10.13) | 0.98 | 87.93 (85.90, 108.96) | 0.27 |
| p-trend** | 0.26 | 0.95 | 0.96 | 0.28 | ||||
Adjusted for home score at six months, smoking status, and maternal age. Pesticides lipid-adjusted with units ng/g lipid.
P-trend based on a scored variable using the median value of each tertile.
P-values based on the comparison between the category with the lowest category (referent).