Table 4.

Association between maternal organochlorine pesticide exposure and communication development scores in daughters at 38 months.^*

Analyte Tertiles (ng/g lipid)	Communicative Adjusted mean (95% CI)	P***	Intelligibility Adjusted mean (95% CI)	P***	Language Adjusted mean (95% CI)	P***
p,p’-DDE (n = 339)
1 ( ≤ 234)	5.06 (4.86, 5.26)		5.82 (5.71, 5.93)		310.60 (305.73, 315.47)
2 (234.1–445)	5.12 (4.95, 5.30)	0.08	5.90 (5.81, 5.99)	0.33	302.80 (298.51, 307.08)	0.96
3 ( ≥ 445)	4.90 (4.73, 5.08)	0.27	5.83 (5.73, 5.93)	0.90	302.62 (298.12, 307.12)	0.03
p-trend**	0.17		0.89		0.05
p,p’-DDT (n = 331)
1 ( ≤ 9.2)	5.22 (5.03, 5.41)		5.78 (5.68, 5.88)		302.98 (298.39, 307.57)
2 (9.21–14.8)	5.07 (4.88, 5.24)	0.08	5.86 (5.76, 5.95)	0.56	309.39 (305.08, 313.71)	0.08
3 ( ≥ 14.8)	4.82 (4.63, 5.02)	0.006	5.90 (5.79, 6.00)	0.11	303.45 (298.78, 308.13)	0.82
p-trend**	0.005		0.13		0.85
HCB (n = 338)
1 ( ≤ 41.9)	4.92 (4.72, 5.12)		5.94 (5.84, 6.05)		309.82 (304.92, 314.73)
2 (41.91–59.9)	5.17 (5.00, 5.34)	0.09	5.85 (5.76, 5.94)	0.34	303.78 (299.61, 307.94)	0.85
3 (> 59.9)	4.95 (4.76, 5.14)	0.88	5.77 (5.67, 5.88)	0.04	303.82 (298.14, 307.51)	0.06
p-trend**	0.99		0.03		0.07
β-HCH (n = 339)
1 (< 39.9)	4.98 (4.76, 5.19)		5.93 (5.81, 6.04)		309.60 (304.38, 314.82)
2 (39.91–56.6)	5.06 (4.89, 5.23)	0.72	5.82 (5.72, 5.91)	0.69	303.94 (299.76, 308.12)	0.91
3 ( ≥ 56.6)	5.02 (4.84, 5.21)	0.77	5.83 (5.73, 5.93)	0.24	303.12 (298.58, 307.66)	0.08
p-trend**	0.87		0.36		0.13

^*Adjusted for home score at 18 months, parity, maternal age and maternal education. Pesticides lipid-adjusted with units ng/g lipid.

^**P-trend based on a scored variable using the median value of each tertile.

^***P-values based on the comparison between the category with the lowest category (referent).