Table 5.
Association between maternal organochlorine pesticide exposure and communication development scores in daughters at 38 months by strata of maternal depression score.*
| Analyte Tertiles (ng/g lipid) |
Communicative Adjusted mean (95% CI) |
P*** | Intelligibility Adjusted mean (95% CI) |
P*** | Language Adjusted mean (95% CI) |
P*** |
|---|---|---|---|---|---|---|
| EPDS ≤ 6 | ||||||
| p,p’-DDT (n = 179) | ||||||
| 1 ( ≤ 9.2) | 5.25 (4.98, 5.52) | 5.78 (5.67, 5.88) | 304.40 (297.32, 311.49) | |||
| 2 (9.21–14.8) | 5.01 (4.79, 5.24) | 0.06 | 5.97 (5.88, 6.06) | 0.83 | 308.81 (302.82, 314.80) | 0.56 |
| 3 ( ≥ 14.8) | 4.71 (4.48, 4.93) | 0.004 | 5.96 (5.87, 6.04) | 0.01 | 306.26 (300.29, 312.23) | 0.71 |
| p-trend** | 0.002 | 0.06 | 0.94 | |||
| EPDS > 6 | ||||||
| p,p’-DDT(n = 146) | ||||||
| 1 ( ≤ 9.2) | 5.22 (4.93, 5.52) | 5.77 (5.58, 5.95) | 301.77 (295.26, 308.28) | |||
| 2 (9.21–14.8) | 5.16 (4.86, 5.46) | 0.46 | 5.70 (5.52, 5.89) | 0.25 | 309.32 (302.73, 315.92) | 0.08 |
| 3 ( ≥ 14.8) | 5.00 (4.64, 5.36) | 0.33 | 5.85 (5.63, 6.07) | 0.49 | 298.72 (290.88, 306.55) | 0.68 |
| p-trend** | 0.31 | 0.46 | 0.65 | |||
Significant interactions (p < 0.05) for EPDS depression score and p,p’-DDT for communicative (pint = 0.007), intelligibility (p-int < 0.0001), and language (pint = 0.003).