Table 8.

Performance metrics across predictive models: observation period ⩽ 5 years after index date (n = 2525; outcomes = 2126).

Metrics	Lasso logistic regression	Naive Bayes	Gradient-boosting machine	Random forest	Neural network	Random	All positive	All negative
Accuracy, %	84.31	60.54	84.15	84.15	83.52	47.39	13.15	86.84
Matthews correlation coefficient, %	15.09	18.74	5.27	5.27	11.97	−6.53	0.00	0.00
Area under curve, %	77.10	64.79	80.69	76.55	78.99	44.14	50.00	50.00

NOTE: outcome was progression to later line of therapy after ⩾ 60 days from the end of a previous one or a stem cell transplantation procedure.