Table 2.
Geometric mean relative expression of HERV-K RNA in ALS cases and controls
HERV-K gag | HERV-K pol | HERV-K env | HERV-K gag | HERV-K pol | HERV-K env | |
---|---|---|---|---|---|---|
Normalisation methoda | GAPDH | GAPDH | GAPDH | XPNPEP1 | XPNPEP1 | XPNPEP1 |
ALS | 1.001 | 1.025 | 0.975 | 0.868 | 0.888 | 0.845 |
Control | 1 | 1 | 1 | 1 | 1 | 1 |
p value | 0.677 | 0.671 | 0.990 | 0.113 | 0.095 | 0.055 |
Statistical significance | NSb | NS | NS | NS | NS | NS |
a Normalisation against either GAPDH or XPNPEP1 reference genes
b NS = the difference was not statistically significant at p < 0.05