Table 2.
Temporal association between changes in pH in the posterior oropharynx detected by Dx-pH (LPR) and GER episodes identified with impedance (episodes of distal and proximal reflux defined as full-column) and pH sensor.
| LPR vs. proximal GER in MII-pH | LPR vs. distal GER in MII-pH | LPR vs. GER in pH monitoring | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| +/+ | -/+ | +/- | +/+ | -/+ | +/- | +/+ | -/+ | +/- | ||
| Value (95% CI) (%) | ||||||||||
| pH level in Dx-pH | <4 | 1.14 (0.00-2.72) | 10.65 (1.24-20.06) | 87.06 (76.35-97.78) | 0.82 (0.00-2.00) | 8.46 (0.07-16.85) | 89.91 (80.69-99.12) | 1.10 (0.00-2.26) | 5.69 (0.00-13.07) | 92.10 (83.14-101.06) |
| <4.5 | 1.69 (0.00-4.12) | 10.47 (1.28-19.65) | 86.15 (74.87-97.42) | 1.28 (0.00-3.28) | 8.23 (0.00-16.45) | 89.22 (79.49-98.96) | 1.43 (0.00-3.08) | 5.78 (0.00-12.97) | 91.37 (81.97-100.77) | |
| <5 | 2.17 (0.00-4.81) | 14.13 (4.68-23.58) | 81.53 (70.02-93.03) | 1.62 (0.00-3.77) | 10.68 (2.24-19.11) | 86.09 (76.13-96.05) | 2.01 (0.10-3.91) | 6.47 (0.00-13.96) | 89.51 (79.64-99.38) | |
| <5.5 | 3.06 (0.40-5.73) | 27.29 (14.58-40.00) | 66.59 (52.05-81.13) | 2.41 (0.03-4.79) | 21.27 (9.60-32.95) | 73.91 (60.76-87.05) | 3.54 (1.50-5.58) | 13.37 (4.50-22.23) | 79.55 (68.11-90.98) | |
| Decrease ≥ 10% | 4.29 (0.65-7.94) | 27.44 (14.88-40.00) | 63.97 (50.14-77.80) | 2.87 (0.09-5.65) | 21.68 (9.51-33.86) | 72.58 (59.44-85.72) | 5.17 (2.51-7.83) | 10.98 (3.00-18.95) | 78.68 (67.83-89.54) | |
LPR: laryngopharyngeal reflux; GER: gastroesophageal reflux; MII-pH: multichannel intraluminal pH-impedance; Dx-pH: pharyngeal pH monitoring; CI: confidence interval; “+”: positive result of the Dx-pH system, impedance, or pH monitoring; “-”: negative result of the Dx-pH system, impedance, or pH monitoring.