Table 1.

Clinical data collected before each injection (T0-T4) and 15 days after the last injection.

Parameters	T0	T1	T2	T3	T4	15 days after the last injection
Masticatory capacity (scores from 0 to 10)∗	3	3	5	7	7	7
Chewing-related pain (scores from 0 to 10)∗∗
min	0	0	0	0	0	0
max	6	9	6	6	6	6
Phonation-related pain (scores from 0 to 10)∗∗
min	0	0	0	0	0	0
max	8	8	8	1	5	5
Rest-related pain (scores from 0 a 10)∗∗
min	0	0	0	0	0	0
max	0	7	0	0	3	3
Level of functional limitation§	4	4	1	1	3	3
Efficacy evaluation∗∗∗	-	1	2	3	1	1
Tolerability evaluation∗∗∗	-	2	3	3	3	3
Mouth-opening ability
Spontaneous	23 mm	23 mm	30 mm	33 mm	25 mm	25 mm
Forced	23 mm	42 mm	35 mm	33 mm	25 mm	27 mm
Right laterality	0	0	0	10 mm	10 mm	10 mm
Protusion	5 mm	5 mm	5 mm	5 mm	3 mm	3 mm
Left laterality	10 mm	10 mm	10 mm	10 mm	10 mm	10 mm

^∗Scores from 0 = inability to chew and only the consumption of semiliquid foods is possible to 10 = optimal chewing capacity of any type of food. ^∗∗NRS scores from 0 = no pain to 10 = intolerable pain. ^§0 = none; 1 = tolerable; 2 = moderate; 3 = intense; 4 = serious. ^∗∗∗0 = light; 1 = tolerable; 2 = moderate; 3 = good; 4 = excellent.