Table 1.
Correlation of RARβ expression with clinicopathological characteristics in patients with colorectal cancer.
| RARβ | n | Low or no expression | High expression | Pearson χ2 | p |
|---|---|---|---|---|---|
| Total | 117 | 81 (69.20) | 36 (30.80) | ||
| Gender | 3.926 | 0.048 ∗ | |||
| Male | 74 | 56 (75.70) | 18 (24.30) | ||
| Female | 43 | 25 (58.10) | 18 (41.90) | ||
| Age at diagnosis (years) | 0.202 | 0.653 | |||
| ≤60 | 42 | 28 (66.70) | 14 (33.30) | ||
| >60 | 75 | 53 (70.70) | 22 (29.30) | ||
| Tumor diameter (cm) | 0.396 | 0.529 | |||
| ≤2 | 9 | 7 (77.80) | 2 (22.20) | ||
| >2 | 105 | 71 (67.60) | 34 (32.40) | ||
| 3a | |||||
| Differentiation | 5.978 | 0.014 ∗ | |||
| Well | 95 | 61 (64.20) | 34 (35.80) | ||
| Poor | 22 | 20 (90.90) | 2 (9.10) | ||
| Lymph node metastasis | 3.772 | 0.052 | |||
| No metastasis | 69 | 43 (62.30) | 26 (37.70) | ||
| Metastasis | 48 | 38 (79.20) | 10 (20.80) | ||
| Distant metastasis (M) | 0.590 | 0.442 | |||
| No metastasis | 111 | 76 (68.50) | 35 (31.50) | ||
| Metastasis | 6 | 5 (83.30) | 1 (16.70) | ||
| Stage grouping with TNM | 6.642 | 0.036 ∗ | |||
| Stage I | 29 | 15 | 14 | ||
| Stage II | 39 | 27 | 12 | ||
| Stage III-IV | 49 | 39 | 10 |
aImmeasurable tumor diameter, 3 cases; ∗p < 0.05.