Table 5.
Clinical characteristics at baseline and change after 24 weeks.
| Characteristics | At baseline, n = 40 | After 24 weeks, n = 40 | P value |
|---|---|---|---|
| Body mass (kg) | 114.5 ± 26.4 | 108.1 ± 25.1 | <0.001 |
| BMI (kg/m2) | 40.9 ± 7.6 | 38.5 ± 7.1 | <0.001 |
| WC (cm) | 122.3 ± 17.0 | 115.7 ± 16.2 | <0.001 |
| НbA1c (%) | 8.4 ± 1.3 | 7.4 ± 1.3 | <0.001 |
| Glucose fasting (mmol/l) | 8.9 ± 1.8 | 6.9 ± 1.5 | 0.004 |
| SBP (mm Hg) | 138.7 ± 14.7 | 129.6 ± 7.9 | 0.001 |
| DBP (mm Hg) | 84.5 ± 8.4 | 78.7 ± 4.9 | 0.001 |
| TC (mmol/l) | 5.2 ± 1.3 | 4.8 ± 1.1 | 0.215 |
| HDL (mmol/l) | 1.0 (0.8; 1.3) | 1.1 (0.9; 1.3) | 0.565 |
| LDL (mmol/l) | 3.1 ± 1.1 | 2.5 ± 1.2 | 0.189 |
| TG (mmol/l) | 1.9 (1.5; 3.2) | 1.7 (1.4; 3.1) | 0.076 |
| C-peptide fasting (ng/ml) | 3.5 ± 1.8 | 3.3 ± 2.1 | 0.569 |
| C-peptide after test∗ (ng/ml) | 5.0 ± 2.8 | 5.4 ± 2.9 | 0.066 |
| НОМА-IR | 7.2 ± 4.4 | 4.7 ± 2.7 | 0.089 |
| НОМА-β | 35.7 (24.5; 61.0) | 35.3 (27.3; 57.3) | 0.716 |
∗2 hours after breakfast in meal tolerance test.