Table 4.

Univariable and multivariable analyses of covariables associated with intracranial progression-free survival

Characteristics	n	Univariate		Multivariate
		HR (95% CI)	P-value	HR (95% CI)	P-value
Number of brain metastasis
>3	70	1.533 (0.969–2.427)	0.068	1.785 (1.110–2.871)	0.017
≤3	34
Therapy method
EGFR-TKI + WBRT	56	0.590 (0.385–0.903)	0.015	0.504 (0.336–0.807)	0.004
EGFR-TKI	48

Abbreviations: TKI, tyrosine kinase inhibitor; WBRT, whole-brain radiotherapy.