Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Mar 15;12:2035–2046. doi: 10.2147/OTT.S188449

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 Cheng et al. This work is published and licensed by Dove Medical Press Limited

The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

PMC Copyright notice

Cellular senescence-inhibited gene (CSIG) levels are expressed differently in different tissues.

Notes: (A) The Cancer Genome Atlas dataset showed that mRNA levels of CSIG in some hepatocellular carcinoma (HCC) tissues (n=8) were up-regulated as compared with their paired para-cancerous tissues (n=8). (B) In other patients, mRNA levels of CSIG in HCC tissues (n=10) were down-regulated as compared with their paired non-tumor tissues (n=10) (TCGA dataset). (C) The proportion of non-recurrent and recurrent cases in low (n=10) and high CSIG-expression groups (n=8). Low CSIG-expression group’s CSIG mRNA levels were lower in HCC tissues than in their paired adjacent non-tumor tissues; high CSIG-expression group’s CSIG mRNA levels in HCC tissues were higher than that in their paired adjacent non-tumor tissues. (D) The proportions of TNM stages in low (n=10) and high CSIG-expression cases (n=8). (E, F) Disease-free survival (DFS) and overall survival (OS) rates were significantly different between low (n=10) and high CSIG-expression groups (n=8) of HCC cases. ^*P<0.05, ^***P<0.001.